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-Structure paper
Title | Identification of a New Class of Glucokinase Activators through Structure-Based Design. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 7669-7678, Year 2013 |
Publish date | Sep 6, 2013 (structure data deposition date) |
Authors | Hinklin, R.J. / Boyd, S.A. / Chicarelli, M.J. / Condroski, K.R. / Dewolf, W.E. / Lee, P.A. / Lee, W. / Singh, A. / Thomas, L. / Voegtli, W.C. ...Hinklin, R.J. / Boyd, S.A. / Chicarelli, M.J. / Condroski, K.R. / Dewolf, W.E. / Lee, P.A. / Lee, W. / Singh, A. / Thomas, L. / Voegtli, W.C. / Williams, L. / Aicher, T.D. |
External links | J. Med. Chem. / PubMed:24015910 |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.9 Å |
Structure data | PDB-4mle: PDB-4mlh: |
Chemicals | ChemComp-GLC: ChemComp-VO1: ChemComp-VO2: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE ACTIVATOR / sugar kinase / allosteric activator / small molecule / TRANSFERASE-TRANSFERASE ACTIVATOR complex |