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-Structure paper
Title | Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 9, Page 677-684, Year 2013 |
Publish date | Jul 19, 2010 (structure data deposition date) |
Authors | Patel, P.D. / Yan, P. / Seidler, P.M. / Patel, H.J. / Sun, W. / Yang, C. / Que, N.S. / Taldone, T. / Finotti, P. / Stephani, R.A. ...Patel, P.D. / Yan, P. / Seidler, P.M. / Patel, H.J. / Sun, W. / Yang, C. / Que, N.S. / Taldone, T. / Finotti, P. / Stephani, R.A. / Gewirth, D.T. / Chiosis, G. |
External links | Nat. Chem. Biol. / PubMed:23995768 |
Methods | X-ray diffraction |
Resolution | 1.47 - 2 Å |
Structure data | PDB-3o0i: PDB-3o2f: |
Chemicals | ChemComp-P54: ChemComp-HOH: ChemComp-IPA: ChemComp-GOL: |
Source |
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Keywords | chaperone/Inhibitor / HSP90 Heat-Shock Proteins / chaperone-Inhibitor complex |