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-Structure paper
Title | Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 5646-5649, Year 2013 |
Publish date | Jan 24, 2013 (structure data deposition date) |
![]() | Biswas, S. / McKenna, R. / Supuran, C.T. |
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Methods | X-ray diffraction |
Resolution | 1.598 Å |
Structure data | ![]() PDB-4iwz: |
Chemicals | ![]() ChemComp-1GO: ![]() ChemComp-ZN: ![]() ChemComp-GOL: ![]() ChemComp-DMS: ![]() ChemComp-HOH: |
Source |
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![]() | LYASE/LYASE INHIBITOR / alpha beta fold / reversible hydration of carbon di oxide to bicarbonate and proton / LYASE-LYASE INHIBITOR complex |