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Structure paper

TitleMalachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
Journal, issue, pagesJ. Mol. Biol., Vol. 425, Page 4595-4613, Year 2013
Publish dateApr 10, 2013 (structure data deposition date)
AuthorsSzent-Gyorgyi, C. / Stanfield, R.L. / Andreko, S. / Dempsey, A. / Ahmed, M. / Capek, S. / Waggoner, A.S. / Wilson, I.A. / Bruchez, M.P.
External linksJ. Mol. Biol. / PubMed:23978698
MethodsX-ray diffraction
Resolution1.93 - 2.45 Å
Structure data

PDB-4k3g:
Immunoglobulin lambda variable domain L5(L89S) fluorogen activating protein
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-4k3h:
Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

ChemComp-1OM:
4-{bis[4-(dimethylamino)phenyl]methyl}phenol

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / immunoglobulin fold / fluorescence / malachite green / o-mannosylation / Thr27 / immune system/inhibitor / fluorescensce / immune system-inhibitor complex

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