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TitleMolecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 135, Page 13796-13803, Year 2013
Publish dateMay 22, 2013 (structure data deposition date)
AuthorsLuh, L.M. / Hansel, R. / Lohr, F. / Kirchner, D.K. / Krauskopf, K. / Pitzius, S. / Schafer, B. / Tufar, P. / Corbeski, I. / Guntert, P. / Dotsch, V.
External linksJ. Am. Chem. Soc. / PubMed:23968199
MethodsNMR (solution)
Structure data

PDB-2m8i:
Structure of Pin1 WW domain
Method: SOLUTION NMR

PDB-2m8j:
Structure of Pin1 WW domain phospho-mimic S16E
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsISOMERASE / Pin1 / WW domain / phospho mimic

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