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-Structure paper
Title | Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 6696-6708, Year 2013 |
Publish date | Mar 12, 2013 (structure data deposition date) |
![]() | Murphy, J.M. / Armijo, A.L. / Nomme, J. / Lee, C.H. / Smith, Q.A. / Li, Z. / Campbell, D.O. / Liao, H.I. / Nathanson, D.A. / Austin, W.R. ...Murphy, J.M. / Armijo, A.L. / Nomme, J. / Lee, C.H. / Smith, Q.A. / Li, Z. / Campbell, D.O. / Liao, H.I. / Nathanson, D.A. / Austin, W.R. / Lee, J.T. / Darvish, R. / Wei, L. / Wang, J. / Su, Y. / Damoiseaux, R. / Sadeghi, S. / Phelps, M.E. / Herschman, H.R. / Czernin, J. / Alexandrova, A.N. / Jung, M.E. / Lavie, A. / Radu, C.G. |
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Methods | X-ray diffraction |
Resolution | 1.89 - 1.94 Å |
Structure data | ![]() PDB-4jlk: ![]() PDB-4l5b: |
Chemicals | ![]() ChemComp-UDP: ![]() ChemComp-1NO: ![]() ChemComp-HOH: ![]() ChemComp-1UX: |
Source |
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![]() | transferase/transferase inhibitor / phosphoryl transfer / phosphorylation / kinase / transferase-transferase inhibitor complex / deoxycytidine kinase |