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Structure paper

TitleRing-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4.
Journal, issue, pagesChem. Res. Toxicol., Vol. 26, Page 1348-1360, Year 2013
Publish dateMar 25, 2013 (structure data deposition date)
AuthorsShanmugam, G. / Minko, I.G. / Banerjee, S. / Christov, P.P. / Kozekov, I.D. / Rizzo, C.J. / Lloyd, R.S. / Egli, M. / Stone, M.P.
External linksChem. Res. Toxicol. / PubMed:23947567
MethodsX-ray diffraction
Resolution2.3 - 2.95 Å
Structure data

PDB-4juz:
Ternary complex of gamma-OHPDG adduct modified dna (zero primer) with dna polymerase iv and incoming dgtp
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-4jv0:
Ring-Opening of the -OH-PdG Adduct in Ternary Complexes with the Sulfolobus solfataricus DNA polymerase Dpo4
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-4jv1:
Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming dgtp
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4jv2:
Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming datp
Method: X-RAY DIFFRACTION / Resolution: 2.74 Å

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

Source
  • sulfolobus solfataricus (archaea)
KeywordsTRANSFERASE/DNA / TERNARY COMPLEX OF DPO4-DNA-DATP / DNA POLYMERASE / DNA ADDUCT / TRANSFERASE-DNA COMPLEX / TERNARY COMPLEX OF DPO4-DNA-DGTP

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