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Structure paper

TitleStructure of the P300 Catalytic Core and Implications for Chromatin Targeting and Hat Regulation
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 20, Page 1040-, Year 2013
Publish dateApr 8, 2013 (structure data deposition date)
AuthorsDelvecchio, M. / Gaucher, J. / Aguilar-Gurrieri, C. / Ortega, E. / Panne, D.
External linksNat. Struct. Mol. Biol. / PubMed:23934153
MethodsX-ray diffraction
Resolution2.799 Å
Structure data

PDB-4bhw:
Structural basis for autoinhibition of the acetyltransferase activity of p300
Method: X-RAY DIFFRACTION / Resolution: 2.799 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-01K:
[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / BROMODOMAIN / PHD DOMAIN / RING DOMAIN / HAT DOMAIN / ENHANCEOSOME

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