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TitleThe toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Journal, issue, pagesNature, Vol. 501, Page 102-106, Year 2013
Publish dateSep 21, 2012 (structure data deposition date)
AuthorsSonati, T. / Reimann, R.R. / Falsig, J. / Baral, P.K. / O'Connor, T. / Hornemann, S. / Yaganoglu, S. / Li, B. / Herrmann, U.S. / Wieland, B. ...Sonati, T. / Reimann, R.R. / Falsig, J. / Baral, P.K. / O'Connor, T. / Hornemann, S. / Yaganoglu, S. / Li, B. / Herrmann, U.S. / Wieland, B. / Swayampakula, M. / Rahman, M.H. / Das, D. / Kav, N. / Riek, R. / Liberski, P.P. / James, M.N. / Aguzzi, A.
External linksNature / PubMed:23903654
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4h88:
Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / C-term mouse prion protein / POM1 FAB

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