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| Title | Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 288, Page 26926-26943, Year 2013 |
| Publish date | Jul 30, 2013 (structure data deposition date) |
Authors | Lauffer, B.E. / Mintzer, R. / Fong, R. / Mukund, S. / Tam, C. / Zilberleyb, I. / Flicke, B. / Ritscher, A. / Fedorowicz, G. / Vallero, R. ...Lauffer, B.E. / Mintzer, R. / Fong, R. / Mukund, S. / Tam, C. / Zilberleyb, I. / Flicke, B. / Ritscher, A. / Fedorowicz, G. / Vallero, R. / Ortwine, D.F. / Gunzner, J. / Modrusan, Z. / Neumann, L. / Koth, C.M. / Lupardus, P.J. / Kaminker, J.S. / Heise, C.E. / Steiner, P. |
External links | J. Biol. Chem. / PubMed:23897821 |
| Methods | X-ray diffraction |
| Resolution | 1.57 - 1.85 Å |
| Structure data | ![]() PDB-4lxz: ![]() PDB-4ly1: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-NA: ![]() ChemComp-PG4: ![]() ChemComp-SHH: ![]() ChemComp-NHE: ![]() ChemComp-HOH: ![]() ChemComp-20Y: |
| Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / deacetylase / Histone / HYDROLASE-HYDROLASE INHIBITOR complex |
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