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Structure paper

TitleStructural and Mechanistic Insights Into Vegfr-3 Ligand Binding and Activation
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 12960-, Year 2013
Publish dateJun 10, 2013 (structure data deposition date)
AuthorsLeppanen, V.-M. / Tvorogov, D. / Kisko, K. / Prota, A.E. / Jeltsch, M. / Anisimov, A. / Markovic-Mueller, S. / Stuttfeld, E. / Goldie, K.N. / Ballmer-Hofer, K. / Alitalo, K.
External linksProc. Natl. Acad. Sci. USA / PubMed:23878260
MethodsX-ray diffraction
Resolution2.5 - 4.201 Å
Structure data

PDB-4bsj:
Crystal structure of VEGFR-3 extracellular domains D4-5
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4bsk:
Crystal structure of VEGF-C in complex with VEGFR-3 domains D1-2
Method: X-RAY DIFFRACTION / Resolution: 4.201 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / LYMPHANGIOGENESIS / ANGIOGENESIS / VASCULAR / IG DOMAIN / GLYCOPROTEIN / RECEPTOR TYROSINE KINASE / DIMERIZATION / TRANSFERASE/HORMONE / TRANSFERASE-HORMONE COMPLEX

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