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Structure paper

TitleStructural mechanism of replication stalling on a bulky amino-polycyclic aromatic hydrocarbon DNA adduct by a y family DNA polymerase.
Journal, issue, pagesJ. Mol. Biol., Vol. 425, Page 4167-4176, Year 2013
Publish dateMay 23, 2012 (structure data deposition date)
AuthorsKirouac, K.N. / Basu, A.K. / Ling, H.
External linksJ. Mol. Biol. / PubMed:23876706
MethodsX-ray diffraction
Resolution2 - 2.6 Å
Structure data

PDB-4fbt:
Dpo4 post-insertion complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4fbu:
Dpo4 polymerase pre-insertion binary complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • sulfolobus solfataricus (archaea)
KeywordsTRANSFERASE/DNA / DNA polymerase / TRANSFERASE-DNA complex

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