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Structure paper

TitleButyrophilin 3A1 binds phosphorylated antigens and stimulates human gamma delta T cells.
Journal, issue, pagesNat. Immunol., Vol. 14, Page 908-916, Year 2013
Publish dateMar 12, 2013 (structure data deposition date)
AuthorsVavassori, S. / Kumar, A. / Wan, G.S. / Ramanjaneyulu, G.S. / Cavallari, M. / El Daker, S. / Beddoe, T. / Theodossis, A. / Williams, N.K. / Gostick, E. ...Vavassori, S. / Kumar, A. / Wan, G.S. / Ramanjaneyulu, G.S. / Cavallari, M. / El Daker, S. / Beddoe, T. / Theodossis, A. / Williams, N.K. / Gostick, E. / Price, D.A. / Soudamini, D.U. / Voon, K.K. / Olivo, M. / Rossjohn, J. / Mori, L. / De Libero, G.
External linksNat. Immunol. / PubMed:23872678
MethodsX-ray diffraction
Resolution1.91 - 2.01 Å
Structure data

PDB-4jkw:
Structure of the extracellular domain of butyrophilin BTN3A1 in complex with Isopentenyl pyrophosphate (IPP)
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-4k55:
Structure of the extracellular domain of butyrophilin BTN3A1 in complex with (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP)
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

Chemicals

ChemComp-IPE:
3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-H6P:
(2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / immunoglobulin superfamily / SIGNALING PROTEIN

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