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Structure paper

TitleAn engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
Journal, issue, pagesMethods, Vol. 65, Page 114-126, Year 2014
Publish dateJun 7, 2013 (structure data deposition date)
AuthorsVafa, O. / Gilliland, G.L. / Brezski, R.J. / Strake, B. / Wilkinson, T. / Lacy, E.R. / Scallon, B. / Teplyakov, A. / Malia, T.J. / Strohl, W.R.
External linksMethods / PubMed:23872058
MethodsX-ray diffraction
Resolution1.92 Å
Structure data

PDB-4l4j:
Crystal structure of fc-fragment of human IgG2-Sigma antibody
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / immunoglobulin fold

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