Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.
Journal, issue, pages	Bioorg. Med. Chem. Lett., Vol. 23, Page 4944-4947, Year 2013
Publish date	Dec 5, 2012 (structure data deposition date)
Authors	Gong, X. / Wang, G. / Ren, J. / Liu, Z. / Wang, Z. / Chen, T. / Yang, X. / Jiang, X. / Shen, J. / Jiang, H. ...Gong, X. / Wang, G. / Ren, J. / Liu, Z. / Wang, Z. / Chen, T. / Yang, X. / Jiang, X. / Shen, J. / Jiang, H. / Aisa, H.A. / Xu, Y. / Li, J.
External links	Bioorg. Med. Chem. Lett. / PubMed:23867165
Methods	X-ray diffraction
Resolution	2.08 - 2.17 Å
Structure data	PDB-4i9z: Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors Method: X-RAY DIFFRACTION / Resolution: 2.08 Å PDB-4ia0: Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors Method: X-RAY DIFFRACTION / Resolution: 2.17 Å
Chemicals	ChemComp-5BA: 5-bromo-2-{5-[(4-methylpiperazin-1-yl)acetyl]-2-propoxyphenyl}-6-(propan-2-yl)pyrimidin-4(3H)-one ChemComp-ZN: Unknown entry ChemComp-MG: Unknown entry ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-HOH: WATER ChemComp-5BB: 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one
Source	homo sapiens (human)
Keywords	HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex