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TitleRabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
Journal, issue, pagesJ. Virol., Vol. 87, Page 10221-10231, Year 2013
Publish dateMar 16, 2013 (structure data deposition date)
AuthorsPan, R. / Sampson, J.M. / Chen, Y. / Vaine, M. / Wang, S. / Lu, S. / Kong, X.P.
External linksJ. Virol. / PubMed:23864637
MethodsX-ray diffraction
Resolution2.033 - 2.6 Å
Structure data

PDB-4jo1:
Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 JR-FL gp120
Method: X-RAY DIFFRACTION / Resolution: 2.033 Å

PDB-4jo2:
Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4jo3:
Crystal structure of rabbit mAb R20 Fab in complex with V3 C-terminus of HIV-1 Consensus B gp120
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4jo4:
Crystal structure of rabbit mAb R20 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

Source
  • oryctolagus cuniculus (rabbit)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / Ig / antibody / IMMUNE SYSTEM-VIRAL PROTEIN complex / IMMUNE SYSTEM

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