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-Structure paper
Title | Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 4501-4505, Year 2013 |
Publish date | Jun 12, 2013 (structure data deposition date) |
![]() | Gangloff, A.R. / Brown, J. / de Jong, R. / Dougan, D.R. / Grimshaw, C.E. / Hixon, M. / Jennings, A. / Kamran, R. / Kiryanov, A. / O'Connell, S. ...Gangloff, A.R. / Brown, J. / de Jong, R. / Dougan, D.R. / Grimshaw, C.E. / Hixon, M. / Jennings, A. / Kamran, R. / Kiryanov, A. / O'Connell, S. / Taylor, E. / Vu, P. |
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Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-4l6s: |
Chemicals | ![]() ChemComp-1WQ: ![]() ChemComp-HOH: |
Source |
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![]() | transferase/transferase inhibitor / DNA single-strand break repair sensitize tumors / DNA repair enzyme / DRD / transferase-transferase inhibitor complex |