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TitleStability and Solubility Engineering of the Ephb4 Tyrosine Kinase Catalytic Domain Using a Rationally Designed Synthetic Library.
Journal, issue, pagesProtein Eng. Des. Sel., Vol. 26, Page 695-, Year 2013
Publish dateOct 13, 2012 (structure data deposition date)
AuthorsOverman, R.C. / Green, I. / Truman, C.M. / Read, J.A. / Embrey, K.J. / Mcalister, M.S.B. / Attwood, T.K.
External linksProtein Eng. Des. Sel. / PubMed:23840071
MethodsX-ray diffraction
Resolution2.11 Å
Structure data

PDB-2yn8:
ephB4 kinase domain inhibitor complex
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

Chemicals

ChemComp-STU:
STAUROSPORINE / anticancer, antifungal, antibiotic, alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / UNPHOSPHORYLATED

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