タイトル | Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. |
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ジャーナル・号・ページ | Science, Vol. 340, Page 1236086-1236086, Year 2013 |
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掲載日 | 2013年4月23日 (構造データの登録日) |
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著者 | Zhou, J. / Lancaster, L. / Donohue, J.P. / Noller, H.F. |
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リンク | Science / PubMed:23812722 |
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手法 | X線回折 |
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解像度 | 3.5 - 4 Å |
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構造データ | PDB-4v9j: 70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state. 手法: X-RAY DIFFRACTION / 解像度: 3.86 Å PDB-4v9k: 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state. 手法: X-RAY DIFFRACTION / 解像度: 3.5 Å PDB-4v9l: 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state. 手法: X-RAY DIFFRACTION / 解像度: 3.5 Å PDB-4v9m: 70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state. 手法: X-RAY DIFFRACTION / 解像度: 4 Å |
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化合物 | ChemComp-GNP: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / Gpp(NH)p / GppNHp, GMPPNP, エネルギー貯蔵分子類似体*YM
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由来 | - thermus thermophilus (バクテリア)
- escherichia coli (大腸菌)
- streptomyces (バクテリア)
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キーワード | RIBOSOME/ANTIBIOTIC / GDPNP / chimeric hybrid state ribosome / translocation intermediate / EF-G / mRNA / tRNA / RIBOSOME-ANTIBIOTIC complex / RIBOSOME / FUSIDIC ACID GDP |
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