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TitleA stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Journal, issue, pagesNature, Vol. 500, Page 93-97, Year 2013
Publish dateMar 18, 2013 (structure data deposition date)
AuthorsSun, X.J. / Wang, Z. / Wang, L. / Jiang, Y. / Kost, N. / Soong, T.D. / Chen, W.Y. / Tang, Z. / Nakadai, T. / Elemento, O. ...Sun, X.J. / Wang, Z. / Wang, L. / Jiang, Y. / Kost, N. / Soong, T.D. / Chen, W.Y. / Tang, Z. / Nakadai, T. / Elemento, O. / Fischle, W. / Melnick, A. / Patel, D.J. / Nimer, S.D. / Roeder, R.G.
External linksNature / PubMed:23812588
MethodsX-ray diffraction
Resolution2.906 Å
Structure data

PDB-4jol:
Complex structure of AML1-ETO NHR2 domain with HEB fragment
Method: X-RAY DIFFRACTION / Resolution: 2.906 Å

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / leukemia; AML1-ETO; HEB; NHR2 domain

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