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Structure paper

TitleSequence determinants of a specific inactive protein kinase conformation.
Journal, issue, pagesChem. Biol., Vol. 20, Page 806-815, Year 2013
Publish dateNov 28, 2012 (structure data deposition date)
AuthorsHari, S.B. / Merritt, E.A. / Maly, D.J.
External linksChem. Biol. / PubMed:23790491
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4i5h:
Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-G17:
N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTransferase/Transferase Inhibitor / MAP kinase / DFG-out / Transferase-Transferase Inhibitor complex

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