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Structure paper

TitleExpanded use of sense codons is regulated by modified cytidines in tRNA.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 10964-10969, Year 2013
Publish dateAug 11, 2012 (structure data deposition date)
AuthorsCantara, W.A. / Murphy, F.V. / Demirci, H. / Agris, P.F.
External linksProc. Natl. Acad. Sci. USA / PubMed:23781103
MethodsX-ray diffraction
Resolution3.2 - 3.298 Å
Structure data

PDB-4gkj:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin.
Method: X-RAY DIFFRACTION / Resolution: 3.298 Å

PDB-4gkk:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

ChemComp-ZN:
Unknown entry

Source
  • thermus thermophilus (bacteria)
  • synthetic (others)
KeywordsRIBOSOME/ANTIBIOTIC / Translation initiation / 5-formylcytidine / RIBOSOME-ANTIBIOTIC complex

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