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-Structure paper
Title | RG7116, a Therapeutic Antibody That Binds the Inactive HER3 Receptor and Is Optimized for Immune Effector Activation. |
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Journal, issue, pages | Cancer Res., Vol. 73, Page 5183-5194, Year 2013 |
Publish date | Jun 26, 2013 (structure data deposition date) |
Authors | Mirschberger, C. / Schiller, C.B. / Schraml, M. / Dimoudis, N. / Friess, T. / Gerdes, C.A. / Reiff, U. / Lifke, V. / Hoelzlwimmer, G. / Kolm, I. ...Mirschberger, C. / Schiller, C.B. / Schraml, M. / Dimoudis, N. / Friess, T. / Gerdes, C.A. / Reiff, U. / Lifke, V. / Hoelzlwimmer, G. / Kolm, I. / Hopfner, K.P. / Niederfellner, G. / Bossenmaier, B. |
External links | Cancer Res. / PubMed:23780344 |
Methods | X-ray diffraction |
Resolution | 2.64 Å |
Structure data | PDB-4leo: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | Transferase/Immune System / Fab fragment / Therapeutic antibody / Her3 receptor / Transferase-Immune System complex |