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-Structure paper
Title | General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 10946-10951, Year 2013 |
Publish date | May 15, 2013 (structure data deposition date) |
Authors | Brinkmann-Chen, S. / Flock, T. / Cahn, J.K. / Snow, C.D. / Brustad, E.M. / McIntosh, J.A. / Meinhold, P. / Zhang, L. / Arnold, F.H. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:23776225 |
Methods | X-ray diffraction |
Resolution | 1.39 - 1.8 Å |
Structure data | PDB-4kqw: PDB-4kqx: |
Chemicals | ChemComp-NAP: ChemComp-TLA: ChemComp-MG: ChemComp-HOH: ChemComp-NAD: ChemComp-HIO: ChemComp-HIS: |
Source |
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Keywords | OXIDOREDUCTASE / Rossmann Fold / Ketol-acid reductoisomerase / acetohydroxyacid isomeroreductase / OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / cofactor switch / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |