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IF

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Structure paper

TitleMIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 10994-10999, Year 2013
Publish dateAug 29, 2012 (structure data deposition date)
AuthorsFan, C. / Rajasekaran, D. / Syed, M.A. / Leng, L. / Loria, J.P. / Bhandari, V. / Bucala, R. / Lolis, E.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:23776208
MethodsX-ray diffraction
Resolution2.33 Å
Structure data

PDB-4gum:
Cystal structure of locked-trimer of human MIF
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / alpha/beta mixture / cytokine and isomerase

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