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TitleCrystal structure of NLRC4 reveals its autoinhibition mechanism
Journal, issue, pagesScience, Vol. 341, Page 172-175, Year 2013
Publish dateMay 25, 2013 (structure data deposition date)
AuthorsHu, Z. / Yan, C. / Liu, P. / Huang, Z. / Ma, R. / Zhang, C. / Wang, R. / Zhang, Y. / Martinon, F. / Miao, D. ...Hu, Z. / Yan, C. / Liu, P. / Huang, Z. / Ma, R. / Zhang, C. / Wang, R. / Zhang, Y. / Martinon, F. / Miao, D. / Deng, H. / Wang, J. / Chang, J. / Chai, J.
External linksScience / PubMed:23765277
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-4kxf:
Crystal structure of NLRC4 reveals its autoinhibition mechanism
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-SO4:
SULFATE ION

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Auto-inhibition / Muti-domain / Innate Immunity / Phosphorylation / ADP BINDING

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