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-Structure paper
Title | Observation of a stable carbene at the active site of a thiamin enzyme. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 9, Page 488-490, Year 2013 |
Publish date | Apr 29, 2013 (structure data deposition date) |
![]() | Meyer, D. / Neumann, P. / Ficner, R. / Tittmann, K. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.06 Å |
Structure data | ![]() PDB-4kgd: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-MG: ![]() ChemComp-PO4: ![]() ChemComp-TPP: ![]() ChemComp-GOL: ![]() ChemComp-K: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / carbanion / structure activity relationship / oxidation-reduction / Umpolung / thiamine diphosphate / reaction intermediate |