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Structure paper

TitleThe making of a slicer: activation of human argonaute-1.
Journal, issue, pagesCell Rep, Vol. 3, Page 1901-1909, Year 2013
Publish dateMay 16, 2013 (structure data deposition date)
AuthorsFaehnle, C.R. / Elkayam, E. / Haase, A.D. / Hannon, G.J. / Joshua-Tor, L.
External linksCell Rep / PubMed:23746446
MethodsX-ray diffraction
Resolution1.754 - 2.101 Å
Structure data

PDB-4kre:
Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Method: X-RAY DIFFRACTION / Resolution: 1.754 Å

PDB-4krf:
Structure of Human Argonaute-1 let-7 complex
Method: X-RAY DIFFRACTION / Resolution: 2.101 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • spodoptera frugiperda (fall armyworm)
KeywordsTRANSCRIPTION/RNA / eukaryotic Argonaute / GENE REGULATION / RNAi / Slicer / TRANSCRIPTION-RNA complex

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