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TitleTracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE.
Journal, issue, pagesBiochemistry, Vol. 52, Page 4507-4516, Year 2013
Publish dateDec 11, 2012 (structure data deposition date)
AuthorsKallio, P. / Patrikainen, P. / Belogurov, G.A. / Mantsala, P. / Yang, K. / Niemi, J. / Metsa-Ketela, M.
External linksBiochemistry / PubMed:23731237
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4icy:
Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptomyces sp. pga64 (bacteria)
KeywordsOXIDOREDUCTASE / FAD-dependent aromatic hydroxylation / monooxygenase / FAD

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