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Structure paper

TitleProtein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Journal, issue, pagesAcs Chem. Biol., Vol. 8, Page 1677-, Year 2013
Publish dateFeb 12, 2013 (structure data deposition date)
AuthorsTortorici, M. / Borrello, M.T. / Tardugno, M. / Chiarelli, L.R. / Pilotto, S. / Ciossani, G. / Vellore, N.A. / Bailey, S.G. / Cowan, J. / O'Connell, M. ...Tortorici, M. / Borrello, M.T. / Tardugno, M. / Chiarelli, L.R. / Pilotto, S. / Ciossani, G. / Vellore, N.A. / Bailey, S.G. / Cowan, J. / O'Connell, M. / Crabb, S.J. / Packham, G.K. / Mai, A. / Baron, R. / Ganesan, A. / Mattevi, A.
External linksAcs Chem. Biol. / PubMed:23721412
MethodsX-ray diffraction
Resolution2.8 - 3.2 Å
Structure data

PDB-3zms:
LSD1-CoREST in complex with INSM1 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

PDB-3zmt:
LSD1-CoREST in complex with PRSFLV peptide
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-3zmu:
LSD1-CoREST in complex with PKSFLV peptide
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3zmv:
LSD1-CoREST in complex with PLSFLV peptide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3zmz:
LSD1-CoREST in complex with PRSFAV peptide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3zn0:
LSD1-CoREST in complex with PRSFAA peptide
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3zn1:
LSD1-CoREST in complex with PRLYLV peptide
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/PEPTIDE / OXIDOREDUCTASE-PEPTIDE COMPLEX / DEMETHYLASE / TRANSCRIPTION FACTOR / CHROMATIN / TRANSCRIPTION / OXIDOREDUCTASE

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