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Structure paper

TitleStructure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Journal, issue, pagesElife, Vol. 2, Page e00594-e00594, Year 2013
Publish dateMar 23, 2013 (structure data deposition date)
AuthorsBanerjee, A. / Lee, A. / Campbell, E. / Mackinnon, R.
External linksElife / PubMed:23705070
MethodsX-ray diffraction
Resolution2.5 - 2.56 Å
Structure data

PDB-4jta:
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4jtc:
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-4jtd:
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-K:
Unknown entry

ChemComp-PGW:
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl / phospholipid*YM

ChemComp-HOH:
WATER

ChemComp-CS:
Unknown entry

Source
  • rattus norvegicus (Norway rat)
  • leiurus quinquestriatus hebraeus (scorpion)
KeywordsTRANSPORT PROTEIN/toxin / potassium channel / pore blocking toxin / protein-protein complex / TRANSPORT PROTEIN-toxin complex / trans-enhanced dissociation effect

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