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Structure paper

TitleStructural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Journal, issue, pagesPlos Pathog., Vol. 9, Page e1003364-e1003364, Year 2013
Publish dateApr 3, 2013 (structure data deposition date)
AuthorsKrey, T. / Meola, A. / Keck, Z.Y. / Damier-Piolle, L. / Foung, S.K. / Rey, F.A.
External linksPlos Pathog. / PubMed:23696737
MethodsX-ray diffraction
Resolution2.05 - 2.22 Å
Structure data

PDB-4jzn:
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-4jzo:
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • hepatitis c virus (isolate h)
Keywordsimmune system/viral protein / Fab fragment / Immunglobulin fold / Antibody / IMMUNE SYSTEM / viral protein-immune system complex / immune system-viral protein complex

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