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TitleActivity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH.
Journal, issue, pagesDna Repair, Vol. 12, Page 535-540, Year 2013
Publish dateFeb 28, 2013 (structure data deposition date)
AuthorsHashimoto, H. / Zhang, X. / Cheng, X.
External linksDna Repair / PubMed:23680598
MethodsX-ray diffraction
Resolution2.582 Å
Structure data

PDB-4jgc:
Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC)
Method: X-RAY DIFFRACTION / Resolution: 2.582 Å

Chemicals

ChemComp-1RT:
4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA / 5-carboxylcytosine; thymine DNA glycosylase; DNA modification; DNA 5mC oxidation; epigenetic regulation / DNA demethylation / 5-carboxylcytosine / HYDROLASE-DNA complex

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