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-Structure paper
Title | Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. |
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Journal, issue, pages | Mol. Biochem. Parasitol., Vol. 189, Page 26-32, Year 2013 |
Publish date | Feb 12, 2013 (structure data deposition date) |
Authors | Koh, C.Y. / Kim, J.E. / Napoli, A.J. / Verlinde, C.L. / Fan, E. / Buckner, F.S. / Van Voorhis, W.C. / Hol, W.G. |
External links | Mol. Biochem. Parasitol. / PubMed:23665145 |
Methods | X-ray diffraction |
Resolution | 2.34 - 2.4 Å |
Structure data | PDB-4j75: PDB-4j76: |
Chemicals | ChemComp-TYM: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | LIGASE / aminoacyl-tRNA synthetase / aaRS / TrpRS / parasite / protein-substrate complex / Rossmann fold / translation / nucleotide binding |