EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank
ジャーナル・号・ページ	J. Biol. Chem., Vol. 288, Page 18260-, Year 2013
掲載日	2013年3月22日 (構造データの登録日)
著者	Bjorkelid, C. / Bergfors, T. / Raichurkar, A.K.V. / Mukherjee, K. / Krishnan, M. / Bandodkar, B. / Jones, T.A.
リンク	J. Biol. Chem. / PubMed:23661699
手法	X線回折
解像度	2.1 - 2.9 Å
構造データ	PDB-4bfs: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1a) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4bft: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1b) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.29 Å PDB-4bfu: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1c) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å PDB-4bfv: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1d) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.29 Å PDB-4bfw: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1e) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.27 Å PDB-4bfx: Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1f) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4bfy: Crystal structure of Mycobacterium tuberculosis PanK in complex with a biaryl inhibitory compound (2a) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4bfz: Crystal structure of Mycobacterium tuberculosis PanK in complex with a biaryl inhibitory compound (2b) and phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å
化合物	ChemComp-ZVS: N-[1-(5-{[2-(4-FLUOROPHENOXY)ETHYL]SULFANYL}-4-METHYL-4H-1,2,4-TRIAZOL-3-YL)ETHYL]-2-(TRIFLUOROMETHYL)BENZAMIDE ChemComp-HOH: WATER / 水 ChemComp-PO4: PHOSPHATE ION / ホスファ-ト / リン酸塩 ChemComp-ZVT: 2-chloro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide ChemComp-ZVU: N-[1-(5-{[(4-fluorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide ChemComp-ZVV: N-[1-(4-methyl-5-{[2-(2-methylphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide ChemComp-ZVW: N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide ChemComp-ZVX: 2,6-difluoro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide ChemComp-ZVY: 2-[4-(4-cyanophenyl)-3-[(4-pyridin-2-ylpiperazin-1-yl)methyl]phenoxy]acetic acid ChemComp-ZVZ: 2-[4-(4-CYANOPHENYL)-3-{[4-(PYRIDIN-2-YL)PIPERAZIN-1-YL]METHYL}PHENOXY]-N-METHYLACETAMIDE
由来	mycobacterium tuberculosis (結核菌)
キーワード	TRANSFERASE (転移酵素) / COA PATHWAY / INHIBITOR (酵素阻害剤) / PANK