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Structure paper

TitleThe structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 69, Page 722-734, Year 2013
Publish dateJun 8, 2011 (structure data deposition date)
AuthorsZhang, X.L. / Tibbits, G.F. / Paetzel, M.
External linksActa Crystallogr. ,Sect. D / PubMed:23633581
MethodsX-ray diffraction
Resolution1.37 - 2 Å
Structure data

PDB-3sd6:
Crystal structure of the amino-terminal domain of human cardiac troponin C in complex with cadmium at 1.4 resolution.
Method: X-RAY DIFFRACTION / Resolution: 1.37 Å

PDB-3swb:
Crystal structure of the amino-terminal domain of human cardiac troponin C in complex with cadmium at 1.7 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-4gje:
Crystal structure of the refolded amino-terminal domain of human cardiac troponin C in complex with cadmium
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4gjf:
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant L29Q in complex with cadmium
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4gjg:
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CD:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsCONTRACTILE PROTEIN / HELIX-LOOP-HELIX EF-HAND MOTIF / CALCIUM SENSOR / CADMIUM BINDING

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