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TitleAtypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 17408-17419, Year 2013
Publish dateOct 8, 2012 (structure data deposition date)
AuthorsKovalenko, O.V. / Olland, A. / Piche-Nicholas, N. / Godbole, A. / King, D. / Svenson, K. / Calabro, V. / Muller, M.R. / Barelle, C.J. / Somers, W. ...Kovalenko, O.V. / Olland, A. / Piche-Nicholas, N. / Godbole, A. / King, D. / Svenson, K. / Calabro, V. / Muller, M.R. / Barelle, C.J. / Somers, W. / Gill, D.S. / Mosyak, L. / Tchistiakova, L.
External linksJ. Biol. Chem. / PubMed:23632026
MethodsX-ray diffraction
Resolution2.34 - 3.04 Å
Structure data

PDB-4hgk:
Shark IgNAR variable domain
Method: X-RAY DIFFRACTION / Resolution: 3.04 Å

PDB-4hgm:
Shark IgNAR Variable Domain
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACE:
ACETYL GROUP

Source
  • homo sapiens (human)
  • squalus acanthias (spiny dogfish)
KeywordsIMMUNE SYSTEM / Ig-fold / human albumin / V-nar

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