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TitleCrystal structure and enzymatic activity of an ADAMTS-13 mutant with the East Asian-specific P475S polymorphism.
Journal, issue, pagesJ. Thromb. Haemost., Vol. 11, Page 1399-1406, Year 2013
Publish dateDec 21, 2011 (structure data deposition date)
AuthorsAkiyama, M. / Nakayama, D. / Takeda, S. / Kokame, K. / Takagi, J. / Miyata, T.
External linksJ. Thromb. Haemost. / PubMed:23621748
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3vn4:
Crystal structure of the exosite-containing fragment of human ADAMTS13 (P475S mutant)
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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