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Structure paper

TitleStructures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations
Journal, issue, pagesNucleic Acids Res., Vol. 41, Page 5524-5532, Year 2013
Publish dateDec 20, 2012 (structure data deposition date)
AuthorsZhang, F. / Tsunoda, M. / Suzuki, K. / Kikuchi, Y. / Wilkinson, O. / Millington, C.L. / Margison, G.P. / Williams, D.M. / Czarina Morishita, E. / Takenaka, A.
External linksNucleic Acids Res. / PubMed:23580550
MethodsX-ray diffraction
Resolution1.54 - 1.94 Å
Structure data

PDB-4ij0:
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-4itd:
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-SR:
STRONTIUM ION

ChemComp-HT:
2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

KeywordsDNA / damaged DNA / O6-carboxymethylguanine / mutagenesis

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