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Structure paper

TitleSirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine
Journal, issue, pagesNature, Vol. 496, Page 110-, Year 2013
Publish dateDec 15, 2012 (structure data deposition date)
AuthorsJiang, H. / Khan, S. / Wang, Y. / Charron, G. / He, B. / Sebastian, C. / Du, J. / Kim, R. / Ge, E. / Mostoslavsky, R. ...Jiang, H. / Khan, S. / Wang, Y. / Charron, G. / He, B. / Sebastian, C. / Du, J. / Kim, R. / Ge, E. / Mostoslavsky, R. / Hang, H.C. / Hao, Q. / Lin, H.
External linksNature / PubMed:23552949
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3zg6:
The novel de-long chain fatty acid function of human sirt6
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-APR:
ADENOSINE-5-DIPHOSPHORIBOSE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / SIRTUIN CLASS III / HDACS NAD DEPENDENT

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