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TitleStructure of a classical broadly neutralizing stem antibody in complex with a pandemic h2 influenza virus hemagglutinin.
Journal, issue, pagesJ. Virol., Vol. 87, Page 7149-7154, Year 2013
Publish dateOct 17, 2012 (structure data deposition date)
AuthorsDreyfus, C. / Ekiert, D.C. / Wilson, I.A.
External linksJ. Virol. / PubMed:23552413
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-4hlz:
Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • influenza a virus
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / neutralizing antibodies / antibody affinity / antigens / epitopes / glycosylation / hemagglutinin glycoproteins / immunoglobulin Fab fragments / H2N2 subtype / influenza vaccines / avian flu / envelope protein / VIRAL PROTEIN-IMMUNE SYSTEM complex

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