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Structure paper

TitleStructural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p.
Journal, issue, pagesJ. Mol. Biol., Vol. 425, Page 1852-1868, Year 2013
Publish dateDec 28, 2012 (structure data deposition date)
AuthorsKobayashi, J. / Matsuura, Y.
External linksJ. Mol. Biol. / PubMed:23541588
MethodsX-ray diffraction
Resolution2.2 - 3.2 Å
Structure data

PDB-3w3t:
Crystal structure of Kap121p
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3w3u:
Crystal structure of Kap121p mutant R349A/Q350A/D353A/E396A/N430K/D438A/N477A
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3w3v:
Crystal structure of Kap121p mutant D353K/E396K/D438K
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3w3w:
Crystal structure of Kap121p bound to Ste12p
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3w3x:
Crystal structure of Kap121p bound to Pho4p
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3w3y:
Crystal structure of Kap121p bound to Nup53p
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3w3z:
Crystal structure of Kap121p bound to RanGTP
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • canis lupus familiaris (dog)
KeywordsPROTEIN TRANSPORT / HEAT repeat / nuclear import / PROTEIN TRANSPORT/DNA BINDING PROTEIN / PROTEIN TRANSPORT-DNA BINDING PROTEIN complex / PROTEIN TRANSPORT/TRANSCRIPTION / PROTEIN TRANSPORT-TRANSCRIPTION complex / PROTEIN TRANSPORT/NUCLEAR PROTEIN / PROTEIN TRANSPORT-NUCLEAR PROTEIN complex

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