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Structure paper

TitleDevelopment of novel molecular probes of the Rio1 atypical protein kinase.
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1834, Page 1292-1301, Year 2013
Publish dateMar 6, 2013 (structure data deposition date)
AuthorsMielecki, M. / Krawiec, K. / Kiburu, I. / Grzelak, K. / Zagorski, W. / Kierdaszuk, B. / Kowa, K. / Fokt, I. / Szymanski, S. / Swierk, P. ...Mielecki, M. / Krawiec, K. / Kiburu, I. / Grzelak, K. / Zagorski, W. / Kierdaszuk, B. / Kowa, K. / Fokt, I. / Szymanski, S. / Swierk, P. / Szeja, W. / Priebe, W. / Lesyng, B. / Laronde-Leblanc, N.
External linksBiochim. Biophys. Acta / PubMed:23523885
MethodsX-ray diffraction
Resolution2.095 Å
Structure data

PDB-4jin:
X-ray crystal structure of Archaeoglobus fulgidus Rio1 bound to (2E)-N-benzyl-2-cyano-3-(pyridine-4-yl)acrylamide (WP1086)
Method: X-RAY DIFFRACTION / Resolution: 2.095 Å

Chemicals

ChemComp-1L7:
(2E)-N-benzyl-2-cyano-3-(pyridin-4-yl)prop-2-enamide

ChemComp-HOH:
WATER

Source
  • archaeoglobus fulgidus (archaea)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / protein kinase / Ribosome Biogenesis / pre-40S / autophosphorylation / TRANSFERASE-TRANSFERASE INHIBITOR complex

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