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TitleStructural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.
Journal, issue, pagesBiochimie, Vol. 95, Page 1379-1385, Year 2013
Publish dateMay 16, 2012 (structure data deposition date)
AuthorsZhang, Y. / Gardberg, A.S. / Edwards, T.E. / Sankaran, B. / Robinson, H. / Varnum, S.M. / Buchko, G.W.
External linksBiochimie / PubMed:23523511
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-4f83:
Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • clostridium botulinum (bacteria)
KeywordsTOXIN / Structural Genomics / NIAID / National Institute of Allergy and Infectious Diseases / Seattle Structural Genomics Center for Infectious Disease / SSGCID / Botulinum neurotoxin / mosaic serotype C/D

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