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Structure paper

TitleA mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing.
Journal, issue, pagesMol. Cell, Vol. 50, Page 104-115, Year 2013
Publish dateFeb 13, 2013 (structure data deposition date)
AuthorsJiao, X. / Chang, J.H. / Kilic, T. / Tong, L. / Kiledjian, M.
External linksMol. Cell / PubMed:23523372
MethodsX-ray diffraction
Resolution1.5 - 1.8 Å
Structure data

PDB-4j7l:
Crystal structure of mouse DXO in complex with PRODUCT RNA AND two MAGNESIUM ions
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4j7m:
Crystal structure of mouse DXO in complex with substrate mimic RNA and calcium ion
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4j7n:
Crystal structure of mouse DXO in complex with M7GPPPG cap
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-UBD:
URIDINE 3',5'-BIS(DIHYDROGEN PHOSPHATE)

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-9MG:
9-METHYLGUANINE

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsHYDROLASE/RNA / Decapping / 5'-3' exoribonuclease / HYDROLASE / HYDROLASE-RNA complex

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