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-Structure paper
Title | Biophysical Fragment Screening of the Beta1-Adrenergic Receptor: Identification of High Affinity Aryl Piperazine Leads Using Structure-Based Drug Design. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 3446-, Year 2013 |
Publish date | Mar 1, 2013 (structure data deposition date) |
![]() | Christopher, J. / Brown, J. / Dore, A. / Errey, J. / Koglin, M. / Marshall, F.H. / Myszka, D. / Rich, R.L. / Tate, C.G. / Tehan, B. ...Christopher, J. / Brown, J. / Dore, A. / Errey, J. / Koglin, M. / Marshall, F.H. / Myszka, D. / Rich, R.L. / Tate, C.G. / Tehan, B. / Warne, T. / Congreve, M. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 2.8 Å |
Structure data | ![]() PDB-3zpq: ![]() PDB-3zpr: |
Chemicals | ![]() ChemComp-Y01: ![]() ChemComp-2CV: ![]() ChemComp-XF5: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-3WC: |
Source |
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![]() | MEMBRANE PROTEIN / GPCR / FRAGMENT SCREENING / ARYL PIPERAZINE / STRUCTURE BASED DRUG DESIGN |