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TitleDiscovery and Structural Characterization of a New Inhibitor Series of HIV-1 Nucleocapsid Function: NMR Solution Structure Determination of a Ternary Complex Involving a 2:1 Inhibitor/NC Stoichiometry.
Journal, issue, pagesJ. Mol. Biol., Vol. 425, Page 1982-1998, Year 2013
Publish dateJan 28, 2013 (structure data deposition date)
AuthorsGoudreau, N. / Hucke, O. / Faucher, A.M. / Grand-Maitre, C. / Lepage, O. / Bonneau, P.R. / Mason, S.W. / Titolo, S.
External linksJ. Mol. Biol. / PubMed:23485336
MethodsNMR (solution)
Structure data

PDB-2m3z:
NMR solution structure of HIV-1 nucleocapsid protein in complex with an inhibitor displaying a 2 inhibitors:1 NC stoichiometry
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-1HF:
(3E)-3-{(2Z)-[(5Z)-5-(furan-2-ylmethylidene)-4-oxo-1,3-thiazolidin-2-ylidene]hydrazinylidene}-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid

Source
  • human immunodeficiency virus type 1
KeywordsVIRAL PROTEIN / HIV-1 NC

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