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TitleViral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Journal, issue, pagesPlos Pathog., Vol. 9, Page e1003173-e1003173, Year 2013
Publish dateMay 12, 2012 (structure data deposition date)
AuthorsMurphy, M.K. / Yue, L. / Pan, R. / Boliar, S. / Sethi, A. / Tian, J. / Pfafferot, K. / Karita, E. / Allen, S.A. / Cormier, E. ...Murphy, M.K. / Yue, L. / Pan, R. / Boliar, S. / Sethi, A. / Tian, J. / Pfafferot, K. / Karita, E. / Allen, S.A. / Cormier, E. / Goepfert, P.A. / Borrow, P. / Robinson, J.E. / Gnanakaran, S. / Hunter, E. / Kong, X.P. / Derdeyn, C.A.
External linksPlos Pathog. / PubMed:23468623
MethodsX-ray diffraction
Resolution1.7 - 2.488 Å
Structure data

PDB-4f57:
Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4f58:
Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient
Method: X-RAY DIFFRACTION / Resolution: 2.488 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Ig / antibody / gp120

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