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-Structure paper
| Title | SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition. |
|---|---|
| Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 20, Page 469-476, Year 2013 |
| Publish date | Aug 14, 2012 (structure data deposition date) |
Authors | Kershaw, N.J. / Murphy, J.M. / Liau, N.P. / Varghese, L.N. / Laktyushin, A. / Whitlock, E.L. / Lucet, I.S. / Nicola, N.A. / Babon, J.J. |
External links | Nat. Struct. Mol. Biol. / PubMed:23454976 |
| Methods | X-ray diffraction |
| Resolution | 3.9 Å |
| Structure data | ![]() PDB-4gl9: |
| Chemicals | ![]() ChemComp-IZA: ![]() ChemComp-PO4: |
| Source |
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Keywords | transferase/transferase inhibitor / kinase inhibitor receptor cytokine signalling / phosphorylation / transferase-transferase inhibitor complex |
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