+Search query
-Structure paper
Title | Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 56, Page 2110-2124, Year 2013 |
Publish date | Oct 30, 2012 (structure data deposition date) |
Authors | Liu, F. / Li, F. / Ma, A. / Dobrovetsky, E. / Dong, A. / Gao, C. / Korboukh, I. / Liu, J. / Smil, D. / Brown, P.J. ...Liu, F. / Li, F. / Ma, A. / Dobrovetsky, E. / Dong, A. / Gao, C. / Korboukh, I. / Liu, J. / Smil, D. / Brown, P.J. / Frye, S.V. / Arrowsmith, C.H. / Schapira, M. / Vedadi, M. / Jin, J. |
External links | J. Med. Chem. / PubMed:23445220 |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | PDB-4hsg: |
Chemicals | ChemComp-KTD: ChemComp-UNX: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / PRMT3 / allosteric inhibitor / Structural Genomics / Structural Genomics Consortium / SGC / TRANSFERASE-TRANSFERASE INHIBITOR complex |